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Concept
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Insulin-Secreting Cells
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Academic Article
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Human, rodent, and canine pancreatic beta-cells express a sodium channel alpha 1-subunit related to a fetal brain isoform.
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Academic Article
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K+ channels: generating excitement in pancreatic beta-cells.
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Academic Article
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NIDDM is associated with loss of pancreatic beta-cell L-type Ca2+ channel activity.
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Academic Article
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Expression and function of pancreatic beta-cell delayed rectifier K+ channels. Role in stimulus-secretion coupling.
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Academic Article
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Baculovirus-mediated gene transfer into pancreatic islet cells.
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Academic Article
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Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism.
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Academic Article
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Defective pancreatic beta-cell glycolytic signaling in hepatocyte nuclear factor-1alpha-deficient mice.
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Academic Article
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TRP genes: candidates for nonselective cation channels and store-operated channels in insulin-secreting cells.
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Academic Article
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Modeling of Ca2+ flux in pancreatic beta-cells: role of the plasma membrane and intracellular stores.
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Academic Article
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Does the glucose-dependent insulin secretion mechanism itself cause oxidative stress in pancreatic beta-cells?
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Academic Article
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Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration.
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Academic Article
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Inositol (1,4,5)-trisphosphate dynamics and intracellular calcium oscillations in pancreatic beta-cells.
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Academic Article
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Protective role for nitric oxide during the endoplasmic reticulum stress response in pancreatic beta-cells.
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Academic Article
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Recovery of islet beta-cell function in streptozotocin- induced diabetic mice: an indirect role for the spleen.
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Academic Article
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Regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic beta-cell: a computational approach.
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Academic Article
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When BAD is good for beta cells.
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Academic Article
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Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice.
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Academic Article
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A model of action potentials and fast Ca2+ dynamics in pancreatic beta-cells.
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Academic Article
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Update in neonatal diabetes.
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Academic Article
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Downstream regulatory element antagonistic modulator regulates islet prodynorphin expression.
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Academic Article
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A brief perspective on insulin production.
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Academic Article
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TRP channels of the pancreatic beta cell.
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Academic Article
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Functional MR microimaging of pancreatic beta-cell activation.
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Academic Article
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Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain.
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Academic Article
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Coupling of metabolic, second messenger pathways and insulin granule dynamics in pancreatic beta-cells: a computational analysis.
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Academic Article
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Adenine nucleotide regulation in pancreatic beta-cells: modeling of ATP/ADP-Ca2+ interactions.
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Academic Article
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The granular chloride channel ClC-3 is permissive for insulin secretion.
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Academic Article
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SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion.
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Academic Article
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Glucose sensing in the pancreatic beta cell: a computational systems analysis.
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Academic Article
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Reactive species, cellular repair and risk factors in the onset of type 2 diabetes mellitus: review and hypothesis.
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Academic Article
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Reversible translocation of EYFP-tagged STIM1 is coupled to calcium influx in insulin secreting beta-cells.
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Academic Article
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In vitro processing and secretion of mutant insulin proteins that cause permanent neonatal diabetes.
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Academic Article
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Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses.
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Academic Article
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Intragranular targeting of syncollin, but not a syncollinGFP chimera, inhibits regulated insulin exocytosis in pancreatic beta-cells.
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Academic Article
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Delayed-rectifier (KV2.1) regulation of pancreatic beta-cell calcium responses to glucose: inhibitor specificity and modeling.
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Academic Article
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Oxidative reactive species in cell injury: Mechanisms in diabetes mellitus and therapeutic approaches.
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Academic Article
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Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice.
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Academic Article
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Bursting and calcium oscillations in pancreatic beta-cells: specific pacemakers for specific mechanisms.
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Academic Article
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Glucose-induced ERM protein activation and translocation regulates insulin secretion.
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Academic Article
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ß-Cell-specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretion.
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Academic Article
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Ion channels and regulation of insulin secretion in human ß-cells: a computational systems analysis.
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Academic Article
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Functional role of serotonin in insulin secretion in a diet-induced insulin-resistant state.
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Academic Article
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Type 2 diabetes and congenital hyperinsulinism cause DNA double-strand breaks and p53 activity in ß cells.
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Academic Article
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Chronic hyperglycemia downregulates GLP-1 receptor signaling in pancreatic ß-cells via protein kinase A.
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Academic Article
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The role of ß cell glucagon-like peptide-1 signaling in glucose regulation and response to diabetes drugs.
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Academic Article
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Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic ß cells.
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Academic Article
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Loss of Liver Kinase B1 (LKB1) in Beta Cells Enhances Glucose-stimulated Insulin Secretion Despite Profound Mitochondrial Defects.
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Academic Article
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Metastatic Insulinoma Following Resection of Nonsecreting Pancreatic Islet Cell Tumor: A Case Report and Review of the Literature.
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Academic Article
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Dynamin 2 regulates biphasic insulin secretion and plasma glucose homeostasis.
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Academic Article
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TCF1 links GIPR signaling to the control of beta cell function and survival.
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Academic Article
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Pancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational Analysis.
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Academic Article
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Resting beta-cells - A functional reserve?
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Academic Article
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Preservation of Reduced Numbers of Insulin-Positive Cells in Sulfonylurea-Unresponsive KCNJ11-Related Diabetes.
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Academic Article
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Simultaneous Real-Time Measurement of the ß-Cell Membrane Potential and Ca2+ Influx to Assess the Role of Potassium Channels on ß-Cell Function.
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Academic Article
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a Cell Function and Gene Expression Are Compromised in Type 1 Diabetes.
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Academic Article
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Human islets expressing HNF1A variant have defective ß cell transcriptional regulatory networks.
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Academic Article
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Deletion of Protein Kinase D1 in Pancreatic ß-Cells Impairs Insulin Secretion in High-Fat Diet-Fed Mice.
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Grant
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K+ Channel Expression in Pancreatic Beta-Cells
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